September 22nd, 2022 | 11:58 CEST
Cardiol Therapeutics, Apple, Nel - Crisis-proof shares, despite inflation
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"[...] As a company dedicated to developing treatments for rare heart diseases, we see this as an opportune moment to contribute to the fight against heart disease and make meaningful strides in improving heart health worldwide. [...]" David Elsley, CEO, Cardiol Therapeutics Inc.
Born in Bielefeld, she studied German, English and psychology. The emergence of the Internet in the early '90s led her from university to training in graphic design and marketing communications. After years of agency work in corporate branding, she switched to publishing and learned her editorial craft at Hubert Burda Media.
Cardiol Therapeutics closes the gap in treatment for corona-related heart disease
US President Joe Biden has officially announced the end of the Corona pandemic. New Zealand and European countries such as France, the Netherlands and Denmark have also lifted measures to protect the public. When a disease such as COVID-19 is more prevalent in a particular population, it is called an endemic. An endemic virus thus circulates permanently in the population and can cause infections. That means that infection from COVID-19 cannot be prevented, and politicians are holding back and relying on the population's own responsibility.
Cardiovascular diseases come into focus both through the consequences of a Corona infection and the side effects of the mRNA vaccines. The latter often occurs in the form of myocarditis or pericarditis, mostly after the second dose by a vaccine from Pfizer or Moderna. Myocarditis is an inflammation of the heart muscle. Pericarditis is inflammation of the outer covering of the heart.
Even young men under 30 years of age have been diagnosed with myocarditis during vaccination. The risk of sudden myocardial infarction is threatening in this segment of the population. Corona will remain a viral disease permanently. So, what can doctors and patients do to protect against the life-threatening consequences of myocarditis?
Until now, acute cases have been treated with the recommended therapies for heart failure. These include diuretics, ACE inhibitors, angiotensin receptor blockers, beta blockers and aldosterone inhibitors. In severe and sudden cases, intensive treatment is often required. Currently, there is no specific treatment for acute myocarditis.
The US-based Company Cardiol Therapeutics has set out to fill precisely this gap with its CardiolRx™ product. The novel therapeutic is a pharmaceutical cannabidiol formulation currently undergoing trial in one of the highest medically approved clinical trials.
The anti-inflammatory effect of cannabidiol in models of cardiovascular disease is a major breakthrough in treating acute myocarditis, according to Cardiol. The abundant experimental evidence suggests that this novel therapy, in the form of the drug CardiolRx™, holds great promise and could receive orphan drug designation. Currently, the share stands at EUR 1.16.
Apple - Latest Apple Watch operating system focuses on heart health
Increasingly, Apple is also specializing in heart health. The iPhone's Health function only gets going together with the Apple Watch. Apple Watch users can enjoy several new, useful running features in the watchOS 9 operating system. These include Cardio Recovery, stride length and ground contact time, among others. The Cardio Recovery feature, previously found under the term "Heart Rate Recovery" on the Apple Watch, will be renamed "Cardio Recovery" with watchOS 9 and iOS 16, perhaps to align with the new Cardio Fitness metric (VO2 max) that will appear in the Health app starting with iOS 16.
Cardio Recovery measures how quickly the heart rate drops immediately after exercise. Like heart rate recovery (HRR), heart rate variability also shows information about heart health. Heart rate is directly related to the autonomic nervous system. The activity of the resting and digestive nervous systems is an important factor in life expectancy. This is reflected by measures of parasympathetic activity, which has been shown to be a critical predictive factor for mortality.
Cardio Recovery is also useful for people who have suffered a heart attack. Recent scientific research shows that Cardio Recovery can improve heart rate recovery by 18-22 beats per minute. Thus, Apple proves how valuable heart health data is to one's physical fitness. In connection with the innovative drug from Cardiol Therapeutics with simultaneous monitoring by, e.g. the Apple Watch under medical supervision, many lives can be healthily prolonged. Medical technology on the wrist is another step of the conglomerate in Cupertino to inspire its users.
Nel - At high speed to green hydrogen technology
The current energy prices for electricity and gas can also quickly come to heart rhythm disturbances. Whether as a company owner who sees his production site at risk or a private investor in an apartment with a gas supply - prices have exploded.
Savvy investors are looking to companies of the future like Nel ASA, based in Norway. The Company specializes in the development of green hydrogen and its production facilities. Green hydrogen is essential in permanently leaving fossil fuels as an energy source. It is given the professional designation of green hydrogen only when no fossil fuel is used in its production..
Water electrolysis is a key technology for Nel to convert renewable energy into hydrogen and has excellent growth potential. Factors driving growth are reduction in capital expenditures and operating costs. This can be achieved through improvements in product design, catalysts, membranes and optimization of operating conditions.
Currently, the review and validation of design changes is a lengthy process that includes long-term durability testing. New protocols for accelerated stress testing will help speed Nel's validation of new materials and cells. This, in turn, will reduce technical product risk and enable the faster introduction of new materials into Nel's commercial electrolyzers.
Nel and the Norwegian Institute for Energy Technology (IFE) have received an injection of EUR 1.2 billion from the Norwegian Research Council to accelerate their testing procedures. The objective is to shorten the time until new green hydrogen technologies can be brought to market. Nel's share price, similar to Cardiol Therapeutics, is currently trading at EUR 1.19.
Many countries are allowing the Corona pandemic to become endemic. Personal responsibility is required from everyone. Heart muscle inflammation or heart disease has increased sharply in the last two years with or without vaccination. Cardiol Therapeutics has a promising drug coming to market that may fill the current gap in treating acute myocarditis. Those who have questions for CEO David Elsley about this will have the opportunity to ask them live on September 27 at the virtual II-Forum. Click here to register for free. Its efficacy is currently being researched in clinical studies according to the highest medical standards. Apple is also increasingly focusing on heart health, enabling its Apple Watch users to gain data sovereignty over their heart rate. Cardiovascular disease is one of the highest causes of death in developed countries. Apple is already in the B2B medical space. The wearable heart computer on the wrist of its B2C users opens up another immeasurable pool of data that could be future-oriented for the development of the Californian company. The Norwegian company Nel is also looking to the future. With a government grant of EUR 1.2 billion, the Company's researchers and engineers are doing everything possible to shorten the development cycles for green hydrogen.
Conflict of interest
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