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January 15th, 2024 | 06:45 CET

Biotech: Corona is back! The doublers are lurking here: BioNTech, Evotec, Defence Therapeutics and Bayer

  • Biotechnology
  • Pharma
  • Covid19
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We had almost forgotten about Corona and the good old flu, but it is back in full swing. Governments are remaining calm and holding on to their regained liberalism. However, Spain is now resorting to drastic measures again to protect vulnerable population groups. A mask is to be compulsory again in all Spanish healthcare facilities due to the increase in respiratory diseases. Health Minister Mónica García had previously failed to convince the Spanish regions of the need to introduce compulsory masks of their own accord. In some parts of the country, hospital emergency rooms are under severe pressure due to high patient numbers. Biotech stocks are showing the first signs of recovery after the sell-off in 2023. We take a look at a few selected stocks with 100% potential.

time to read: 4 minutes | Author: André Will-Laudien

Table of contents:

    David Elsley, CEO, Cardiol Therapeutics Inc.
    "[...] As a company dedicated to developing treatments for rare heart diseases, we see this as an opportune moment to contribute to the fight against heart disease and make meaningful strides in improving heart health worldwide. [...]" David Elsley, CEO, Cardiol Therapeutics Inc.

    Full interview


    BioNTech versus Bayer - Who will bounce back sooner?

    The heydays of BioNTech and Bayer are seemingly over, as both stocks have suffered a severe downturn on the capital markets, although the balance sheet details do not sound so bad. Although BioNTech reported a sharp decline in sales from EUR 18 billion in 2022 to just EUR 4.1 billion in 2023 due to reduced vaccine sales, the Mainz-based company is still sitting on a cash position of a good EUR 17 billion. Bayer's revenue fell by a noticeable 6% from EUR 50.7 billion to EUR 47.6 billion, with the ongoing glyphosate lawsuits in the US still having a negative impact. The Leverkusen-based company share price fell back to EUR 30.25. Since the high of around EUR 140 in 2016, 80% of the valuation has been lost. In addition, the Group's debt has doubled in the same period to currently EUR 92 billion. Despite ongoing challenges, Bayer can maintain its high dividend payout of over 6% thanks to current earnings.

    Analysts on the Refinitiv Eikon platform are divided. In the case of BioNTech, there are as many as 8 "Buy" recommendations out of 17 available ratings, but the average price target is only set at USD 120 - 15% above the current price. For Bayer, the experts are even more skeptical, with only 7 out of 24 giving a "Buy" recommendation, but still with a consensus price target of around EUR 45.50. This promises a potential of at least 34% over the next 12 months. In chart terms, overcoming the EUR 115 mark for BioNTech would turn the signal to green, which is only the case for Bayer shares when the EUR 52 mark is conquered.

    Defence Therapeutics - AccuTOX® shows efficacy in lung cancer

    Canadian biotech specialist Defence Therapeutics has launched another formulation of its successfully tested cancer drug AccuTOX® in the new year. The drug, known as ACCUM-002TM Dimer CDCA-SV40, has proven to be effective in the treatment of lung tumors, thus extending the scope of AccuTOX® to the treatment of solid tumors. AccuTOX® represents an optimization of the Accum™ molecule and platform technology developed by Defence.

    In recent studies, the compound was shown to have improved therapeutic properties and a broader range of applications in cancer treatments. It successfully killed more than a dozen murine and human cancer cell lines. Prospectively, such a therapy could be used as an alternative to surgery or chemotherapy. When initially administered intranasally, AccuTOX® showed a strong effect in inhibiting tumor growth of existing lung nodules in mice. Defence used a Kent Scientific Corporation nebulizer to administer its drug in the least invasive way possible. When used as a monotherapy, AccuTOX® significantly inhibited the growth of lung nodules. This effect is further enhanced when combined with the immune checkpoint inhibitor anti-PD1.

    According to Precedence Research, the global market for cancer therapeutics is expected to reach around USD 393 billion by 2032, starting from USD 164 billion in 2022. Defence would like to participate disproportionately in the expected growth. To this end, CAD 2.7 million was successfully raised via a capital increase at the end of last week. Since December 19, 2023, the share has also been tradable on the US OTCQB over-the-counter segment under the symbol "DTCFF". With just under 46 million shares, the Company is currently valued at EUR 68.5 million. This is a very low valuation given the advanced stage of development of the ACCUM™ platform. Defence could become a top performer in the immuno-oncology peer group in 2024.

    Evotec - Long-time CEO Lanthaler leaves the Company

    There is a sell-off mood at the German biotech company Evotec. The resignation of the previous CEO, Werner Lanthaler, continues to weigh heavily. Mario Polywka has now taken over the position of CEO for the time being; he was previously a member of the Supervisory Board and previously active as COO. Meanwhile, the search for a new CEO is in full swing. Apart from personnel matters, there is further news. Evotec has joined an American foundation that focuses on research into inflammatory bowel diseases. The collaboration with the Crohn's & Colitis Foundation IBD Therapeutics Incubator program will leverage Evotec's research and development platforms to advance drug discovery for two innovative targets.

    The experts of the Canadian bank RBC have left their rating on Evotec at "Sector Perform" and a price target of EUR 18.60. A milestone payment from the US pharmaceutical company Bristol-Myers Squibb significantly reduces the risk of achieving the next operating targets. Warburg also remains on the buy side with a price target of EUR 29. The annual figures for 2023 will be published on April 24, which is still relatively far away. The fundamental opportunities for the Hamburg-based company, therefore, remain good, but volatility is likely to remain high due to a large number of incoming reports. The recapture of the 200-day line at around EUR 19.70 would provide an initial positive technical signal.

    Evotec fell by almost 30% after long-time CEO Werner Lanthaler resigned. Defence, BioNTech and Bayer have bottomed out in recent weeks. A technical turnaround should be imminent here. Source: Refinitiv Eikon from 12.01.2024

    The biotech sector has had a subdued start to the year. Smaller technical consolidations can be seen in Bayer, BioNTech and Defence Therapeutics. Fundamentally, Defence is making good progress in the field of lung cancer, while the departure of CEO Werner Lanthaler leaves a significant gap.

    Conflict of interest

    Pursuant to §85 of the German Securities Trading Act (WpHG), we point out that Apaton Finance GmbH as well as partners, authors or employees of Apaton Finance GmbH (hereinafter referred to as "Relevant Persons") currently hold or hold shares or other financial instruments of the aforementioned companies and speculate on their price developments. In this respect, they intend to sell or acquire shares or other financial instruments of the companies (hereinafter each referred to as a "Transaction"). Transactions may thereby influence the respective price of the shares or other financial instruments of the Company.
    In this respect, there is a concrete conflict of interest in the reporting on the companies.

    In addition, Apaton Finance GmbH is active in the context of the preparation and publication of the reporting in paid contractual relationships.
    For this reason, there is also a concrete conflict of interest.
    The above information on existing conflicts of interest applies to all types and forms of publication used by Apaton Finance GmbH for publications on companies.

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    Der Autor

    André Will-Laudien

    Born in Munich, he first studied economics and graduated in business administration at the Ludwig-Maximilians-University in 1995. As he was involved with the stock market at a very early stage, he now has more than 30 years of experience in the capital markets.

    About the author

    Related comments:

    Commented by Fabian Lorenz on May 16th, 2024 | 08:00 CEST

    Share price shock at Siemens Energy! What are BioNTech and Cardiol Therapeutics doing?

    • Biotechnology
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    The Siemens Energy share has been one of the surprises of recent months. It has more than doubled since the beginning of the year. Is a crash now imminent? Yes, if you believe Bernstein. Their analysts are shocking us with a horror price target. The Cardiol Therapeutics share performed even better than Siemens Energy in 2024. Despite the 150% rally, analysts see upside potential for the cardiovascular disease specialist. Things will get really exciting at the beginning of June when new study results are due. BioNTech, on the other hand, is currently failing to convince analysts. Reactions to the latest quarterly figures were modest.


    Commented by Stefan Feulner on May 14th, 2024 | 07:30 CEST

    Bayer, Defence Therapeutics, Novavax - Major events

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    The biotechnology sector is still on the move and is currently characterized by a high degree of volatility. For instance, BioNTech, a former star during the pandemic, reported a net loss of EUR 315 million in the first quarter. The Mainz-based biotech now wants to focus more on the development of its cancer drugs due to the slump in demand for COVID-19 vaccines. However, for years, innovative, undiscovered companies have existed in this billion-dollar market that could, with their technologies, become the new high-flyers in the biotech industry.


    Commented by Fabian Lorenz on May 9th, 2024 | 08:00 CEST

    Stocks facing revaluation! Nel ASA, Bayer, Power Nickel with potential

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    Relief for Bayer. In the US, the Company has won a victory in the dispute over compensation for illnesses caused by the chemical PCB. Is it groundbreaking and the start of a revaluation of the share? A revaluation already seems to be underway at Power Nickel. Following sensational drilling results, the share price soared. Surprisingly, gold, silver and copper were also found. Against this backdrop, the share appears to be favorably valued. Does this also apply to Nel? After all, the share price has risen by around 20% in just a few weeks. Is there new hope for the hydrogen pioneer? Or are today's figures from industry peer Plug Power threatening a new sell-off?