March 10th, 2021 | 09:27 CET
BioNTech, CureVac, Cardiol Therapeutics: Biotech rockets off the launchpad
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"[...] As a company dedicated to developing treatments for rare heart diseases, we see this as an opportune moment to contribute to the fight against heart disease and make meaningful strides in improving heart health worldwide. [...]" David Elsley, CEO, Cardiol Therapeutics Inc.
BioNTech: What's next for the vaccine hopeful?
The BioNTech share was an investor favorite for many months. Even today, the stock still has a lot to offer fundamentally. The Company is a leader in mRNA technology and was the first to develop a vaccine against Covid-19 successfully. Currently, it shows that it has paid off to break new ground in vaccine development. BioNTech's preparation is extremely effective and, almost more importantly, can interrupt chains of infection. One of the reasons why more and more experts are now advocating that younger people should also be vaccinated with BioNTech. If people with many contacts are vaccinated with it, it can have a significant epidemiological effect, they believe.
In the stock market, the stock has lost about 27% in the past three months. Given the increase in the preceding months, this is not a significant blow, but momentum seems to have left the share. It is currently rather unlikely that the share will rush from one high to the next as it did in the fall. Even if BioNTech is an excellent company, the share is currently lacking esprit.
CureVac: Share does not gain momentum
Similar to BioNTech, the Tübingen-based competitor CureVac is also suffering. The Company has also focused on mRNA technology and has developed an effective vaccine currently undergoing approval procedures within the EU. A partner for the production of the vaccine has also been found in Novartis. Together, the two companies plan to bring 50 million doses to market this year. In 2022, the aim is to produce a further 200 million vaccine doses. On a three-month view, however, CureVac's stock is underperforming BioNTech, losing about 37%. It seems that once the first vaccines are ready for the market, the fantasy around the share fades.
Cardiol Therapeutics: Story and valuation are right here
Nevertheless, Covid-19 and its mutations will be with us for many years to come. The vaccine manufacturers mentioned above will also adapt their preparations and bring new versions to market. It is similar to what is already happening with flu vaccines. In the future, one focus is also likely to be on mitigating severe courses or successfully treating patients with various pre-existing conditions. The biotech Company Cardiol Therapeutics is developing its active ingredient CardiolRx™ to treat inflammatory heart disease in this context. For the treatment of sequelae in the course of Covid-19 disease, the compound has already passed through clinical phase 1 and a Phase 2/3 trial is commencing imminently. Studies are also planned for other indications, such as acute myocarditis and diastolic heart failure. The biotech company relies on a highly concentrated dose of cannabidiol for its active ingredient, ensuring that it is highly effective despite being taken orally. Pre-clinical studies show significant effects on diseased heart tissue. Cardiovascular complications are frequent consequences of severe courses in connection with Covid-19 and lead to many deaths independently of the pandemic.
Cardiol Therapeutics has also developed a commercial CBD preparation in addition to CardiolRx™. It is distinguished by its remarkable purity and freedom from THC. These preparations are particularly popular with elderly patients. With this second pillar, the biotech company now wants to take off on the stock market. Only recently, Cardiol Therapeutics announced that it has submitted its application to be listed on the Nasdaq, subject to the approval of the Nasdaq and the satisfaction of all applicable listing criteria and requirements. At the same time, the Company succeeded in raising an additional USD 10 million in capital through subscription rights. Cardiol Therapeutics thus has financial leeway and is unlikely to raise additional capital in the near future. The listing on Nasdaq should also ensure that the company's relative undervaluation compared to other biotech companies becomes even more visible on the market. A few weeks ago, the biotech company GW Pharmaceuticals, which also uses active ingredients from the cannabis plant, was acquired in the USA for more than USD 7 billion. Cardiol Therapeutics' market capitalization is just over USD 100 million.
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