Coinbase, Defence Therapeutics, Palantir – Forward-looking decisions

Defence Therapeutics – Consolidation complete

The US president's announcement of punitive tariffs on "Liberation Day" sent stock markets around the world reeling, with the biotech sector also being dragged down in the wake, presenting investors with another buying opportunity. Shares in Defence Therapeutics, a research company working to develop the next generation of vaccines and ADC products using its proprietary and patented Accum® platform, consolidated after a strong rise of around 237% to an interim high of CAD 1.66, closed the upward gap that had opened at CAD 0.85 and has since turned north again.

With the sustained break above the downward trend established in December at CAD 0.90, the path to the 200 EMA at CAD 1.02 would be clear in the short term. The next major resistance would then be at CAD 1.30. Both MACD and RSI gave a buy signal at a low level last week, indicating that there is still significant upside potential.

Accum® technology addresses a key problem in modern therapies: many active ingredients remain in cell compartments and do not reach their target location. Accum® enables more targeted release, increases efficacy by a factor of 10, and thus allows for lower dosages. Its cross-industry applicability, from cancer vaccines to mRNA therapies, opens up access to billion-dollar markets.

With patents until 2043, Defence has not only secured its technological leadership but also laid the foundation for licensing and recurring revenues. Dr. Elias Theodorou was recently introduced as the new COO. With 25 years of research expertise, he will play a key role in advancing the commercialization of the technology.

Coinbase – Buy signals generated

After a downward trend since January, Bitcoin rebounded from its interim low of USD 74,434 and dynamically regained the USD 90,000 mark last week. Compared to the stock market, Bitcoin & Co. have shown relative strength since Trump's tariffs were announced. Marking new highs again in the coming weeks is, therefore, not unlikely.

The crypto exchange Coinbase once again benefited from the rising prices. After confirming a double bottom at USD 146.12, the stock was able to start a new upward momentum and break through the USD 200 mark. The trend-following indicator MACD is at "Buy", while the relative strength index RSI is currently at a "Neutral" 61 points and still has significant upside potential.

The 100 and 200 EMAs are in the USD 220 range. A sustained break above the downward trend established since the beginning of December 2024, currently at USD 245, would already generate price targets beyond the USD 300 mark. Downward support is currently in the USD 180 range. A drop below this mark, on the other hand, would be a clear bearish sign.

PayPal – Revolutionary cooperation

Another reason for the upward swing in Coinbase shares was a forward-looking cooperation with the leading US payment provider PayPal, which could revolutionize digital payments in the future. The partnership aims to strengthen the distribution and functionality of the PayPal USD (PYUSD) stablecoin. The goal is to make it easier for consumers, businesses, and institutions to access digital currencies with the stability of USD-backed assets.

As part of the expanded collaboration, Coinbase users can buy, sell, and trade PYUSD without platform fees and redeem it at a 1:1 ratio against the US dollar on Coinbase platforms.

In addition, PayPal and Coinbase plan to work together on innovations to advance stablecoin-based solutions for global money transfers, particularly in the area of commerce. They also intend to explore new use cases for PYUSD in decentralized finance (DeFi) and on-chain platforms.

PayPal President and CEO Alex Chriss emphasized the importance of this partnership, which builds on a shared history of making cryptocurrencies more accessible to users. Brian Armstrong, CEO of Coinbase, highlighted that the partnership offers an opportunity to leverage PayPal's large consumer and merchant accounts base for the global adoption of stablecoins.

This new agreement builds on an earlier collaboration in 2021 that allowed Coinbase users to use PayPal accounts for instant funding of cryptocurrency purchases and fiat withdrawals.

PayPal USD is a stablecoin issued by Paxos Trust Company and is fully backed by US dollar deposits, US Treasury securities, and similar liquid assets. PYUSD can be traded at a fixed rate of USD 1.00 per token via PayPal and Venmo.

Cryptocurrencies continued their upward momentum last week. This allowed the Coinbase crypto exchange to regain the USD 200 mark. A revolutionary partnership with payment provider PayPal also provided positive impetus. Defence Therapeutics consolidated in line with the overall market correction, with indicators once again signaling a buy.